Samuel L Jackson is urging men to "get themselves checked out" as part of a new fundraising campaign to raise awareness of male cancer.
The Captain America star has tweeted a video to his millions of followers with advice, including seeing a doctor if symptoms occur.
"By not getting checked you could lose those balls. Hell - you could lose your life! So boys, don't be dumb. If you've really got balls, show them to your doctor," he says.
Jackson has been supporting the One For The Boys campaign which has teamed up with the crowdfunding website MyGoodness.com to run an online raffle to raise money.
He says: "Fact: 30% cent more men die of cancer than women. Whaaat? Get outta here! That's right: 30%. Why? Because they don't get themselves checked out early enough.
Jackson stars in Captain America with Chris Evans and Scarlett Johansson"They don't want to hear or talk about it, because it ain't the manly thing to do. They're too macho."
Entrants will have the chance to hang-out with the Hollywood actor in London for a day as one of many "money can't buy" experiences.
"Hanging out with Samuel L Jackson for a day certainly constitutes a 'money-can't-buy' experience in my book," says MyGoodness.com co-founder Nathalie Verrando.
Co-founder Severine Balick added: "It's fantastic that someone of Samuel's status is prepared to give his valuable time for such a great cause in this way.
"The lucky winner will no doubt dine out on this experience for years to come!"
On Saturday Jackson tweeted a picture of himself with West Ham footballer Dylan Tombides who died of testicular cancer aged just 20.
The pair met at a cancer awareness event in London in November.
"Gone too soon Dylan Tombides. It was a pleasure to have met you. My thoughts are with your family," he wrote.
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